2IJ5

Crystal structure of cytochrome P450 CYP121, P212121 space group

Summary for 2IJ5

Entry DOI	10.2210/pdb2ij5/pdb
Related	1N40 2IJ7
Descriptor	Cytochrome P450 121, SULFATE ION, PROTOPORPHYRIN IX CONTAINING FE, ... (4 entities in total)
Functional Keywords	tuberculosis, cyp121, cytochrome p450, azole ligation, fluconazole, oxidoreductase
Biological source	Mycobacterium tuberculosis
Cellular location	Cytoplasm (By similarity): P0A514
Total number of polymer chains	6
Total formula weight	264110.48
Authors	Roujeinikova, A.,Leys, D. (deposition date: 2006-09-29, release date: 2006-11-07, Last modification date: 2023-08-30)
Primary citation	Seward, H.E.,Roujeinikova, A.,McLean, K.J.,Munro, A.W.,Leys, D. Crystal structure of the Mycobacterium tuberculosis P450 CYP121-fluconazole complex reveals new azole drug-P450 binding mode. J.Biol.Chem., 281:39437-39443, 2006 Cited by PubMed: 17028183 DOI: 10.1074/jbc.M607665200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.6 Å)

Structure validation