2IAE
Crystal structure of a protein phosphatase 2A (PP2A) holoenzyme.
Summary for 2IAE
Entry DOI | 10.2210/pdb2iae/pdb |
Related | 1B3U |
Related PRD ID | PRD_000212 |
Descriptor | Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform, Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform, Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform, ... (5 entities in total) |
Functional Keywords | protein phosphorylation, phosphatase, pp2a, b56, tumor suppressor, methylation, hydrolase, toxin, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Mus musculus (house mouse) More |
Cellular location | Cytoplasm : Q76MZ3 P67775 Nucleus: Q13362 |
Total number of polymer chains | 8 |
Total formula weight | 300705.13 |
Authors | |
Primary citation | Cho, U.S.,Xu, W. Crystal structure of a protein phosphatase 2A heterotrimeric holoenzyme. Nature, 445:53-57, 2007 Cited by PubMed: 17086192DOI: 10.1038/nature05351 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.5 Å) |
Structure validation
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