2HTF
The solution structure of the BRCT domain from human polymerase reveals homology with the TdT BRCT domain
Summary for 2HTF
Entry DOI | 10.2210/pdb2htf/pdb |
NMR Information | BMRB: 7259 |
Descriptor | DNA polymerase mu (1 entity in total) |
Functional Keywords | brct domain, alpha-beta-alpha sandwich, transferase |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus (By similarity): Q9NP87 |
Total number of polymer chains | 1 |
Total formula weight | 11420.02 |
Authors | DeRose, E.F.,Clarkson, M.W.,Gilmore, S.A.,Ramsden, D.A.,Mueller, G.A.,London, R.E.,Lee, A.L. (deposition date: 2006-07-25, release date: 2007-02-27, Last modification date: 2024-05-29) |
Primary citation | DeRose, E.F.,Clarkson, M.W.,Gilmore, S.A.,Galban, C.J.,Tripathy, A.,Havener, J.M.,Mueller, G.A.,Ramsden, D.A.,London, R.E.,Lee, A.L. Solution structure of polymerase mu's BRCT Domain reveals an element essential for its role in nonhomologous end joining. Biochemistry, 46:12100-12110, 2007 Cited by PubMed: 17915942DOI: 10.1021/bi7007728 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
Download full validation report