2HEO
General Structure-Based Approach to the Design of Protein Ligands: Application to the Design of Kv1.2 Potassium Channel Blockers.
Summary for 2HEO
Entry DOI | 10.2210/pdb2heo/pdb |
Related | 1J75 |
Descriptor | 5'-D(*TP*CP*GP*CP*GP*CP*G)-3', Z-DNA binding protein 1 (3 entities in total) |
Functional Keywords | protein dlm1-z-dna complex, immune system-dna complex, immune system/dna |
Biological source | Mus musculus (house mouse) |
Total number of polymer chains | 4 |
Total formula weight | 19106.01 |
Authors | Magis, C.,Gasparini, S.,Charbonnier, J.B.,Stura, E.,Le Du, M.H.,Menez, A.,Cuniasse, P. (deposition date: 2006-06-21, release date: 2006-11-21, Last modification date: 2023-08-30) |
Primary citation | Magis, C.,Gasparini, D.,Lecoq, A.,Le Du, M.H.,Stura, E.,Charbonnier, J.B.,Mourier, G.,Boulain, J.C.,Pardo, L.,Caruana, A.,Joly, A.,Lefranc, M.,Masella, M.,Menez, A.,Cuniasse, P. Structure-based secondary structure-independent approach to design protein ligands: Application to the design of Kv1.2 potassium channel blockers. J.Am.Chem.Soc., 128:16190-16205, 2006 Cited by PubMed: 17165772DOI: 10.1021/ja0646491 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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