2HDU

AmpC beta-lactamase in complex with 2-acetamidothiophene-3-carboxylic acid

Summary for 2HDU

Entry DOI	10.2210/pdb2hdu/pdb
Related	2HDQ 2HDR 2HDS
Descriptor	Beta-lactamase, 2-(ACETYLAMINO)THIOPHENE-3-CARBOXYLIC ACID, POTASSIUM ION, ... (5 entities in total)
Functional Keywords	ampc beta-lactamase fragment-based drug design, hydrolase
Biological source	Escherichia coli K12
Cellular location	Periplasm: P00811
Total number of polymer chains	2
Total formula weight	80791.51
Authors	Babaoglu, K.,Shoichet, B.K. (deposition date: 2006-06-20, release date: 2006-11-07, Last modification date: 2017-10-18)
Primary citation	Babaoglu, K.,Shoichet, B.K. Deconstructing fragment-based inhibitor discovery Nat.Chem.Biol., 2:720-723, 2006 Cited by PubMed: 17072304 DOI: 10.1038/nchembio831 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.49 Å)

Structure validation