2HAN

Structural basis of heterodimeric ecdysteroid receptor interaction with natural response element hsp27 gene promoter

Summary for 2HAN

• Entry DOI: 10.2210/pdb2han/pdb
• Descriptor: 5'-D(*CP*AP*AP*GP*GP*GP*TP*TP*CP*AP*AP*TP*GP*CP*AP*CP*TP*TP*GP*T)-3', 5'-D(*GP*AP*CP*AP*AP*GP*TP*GP*CP*AP*TP*TP*GP*AP*AP*CP*CP*CP*TP*T)-3', Protein ultraspiracle, ... (6 entities in total)
• Functional Keywords: transcription regulation, transcription factor, dna-binding, nuclear protein, nuclear receptor, zinc finger, transcription-dna complex, transcription/dna
• Biological source: Drosophila melanogaster (fruit fly); More
• Cellular location: Nucleus: P20153 P34021
• Total number of polymer chains: 4
• Total formula weight: 36867.86

Authors

Jakob, M.,Kolodziejczyk, R.,Orlowski, M.,Krzywda, S.,Kowalska, A.,Dutko-Gwozdz, J.,Gwozdz, T.,Kochman, M.,Jaskolski, M.,Ozyhar, A. (deposition date: 2006-06-13, release date: 2007-05-22, Last modification date: 2023-08-30)

• Primary citation: Jakob, M.,Kolodziejczyk, R.,Orlowski, M.,Krzywda, S.,Kowalska, A.,Dutko-Gwozdz, J.,Gwozdz, T.,Kochman, M.,Jaskolski, M.,Ozyhar, A.; Novel DNA-binding element within the C-terminal extension of the nuclear receptor DNA-binding domain.; Nucleic Acids Res., 35:2705-2718, 2007; PubMed: 17426125; DOI: 10.1093/nar/gkm162

Experimental method

X-RAY DIFFRACTION (1.95 Å)