2H59

Sir2 H116A-deacetylated p53 peptide-3'-o-acetyl ADP ribose

Summary for 2H59

Entry DOI	10.2210/pdb2h59/pdb
Related	2H4F 2H4H 2H4J
Descriptor	NAD-dependent deacetylase, Cellular tumor antigen p53, ZINC ION, ... (6 entities in total)
Functional Keywords	rossmann fold, zn binding domain, hydrolase
Biological source	Thermotoga maritima More
Cellular location	Cytoplasm : Q9WYW0
Total number of polymer chains	4
Total formula weight	60493.92
Authors	Hoff, K.G.,Avalos, J.L.,Sens, K.,Wolberger, C. (deposition date: 2006-05-25, release date: 2006-09-05, Last modification date: 2023-08-30)
Primary citation	Hoff, K.G.,Avalos, J.L.,Sens, K.,Wolberger, C. Insights into the Sirtuin Mechanism from Ternary Complexes Containing NAD(+) and Acetylated Peptide. Structure, 14:1231-1240, 2006 Cited by PubMed: 16905097 DOI: 10.1016/j.str.2006.06.006 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation