2H2G

The Structural Basis of Sirtuin substrate affinity

Summary for 2H2G

• Entry DOI: 10.2210/pdb2h2g/pdb
• Descriptor: NAD-dependent deacetylase, HISTONE H3 PEPTIDE, ZINC ION, ... (4 entities in total)
• Functional Keywords: h3-k115ac, sir2, sir2tm, sirtuin, sirt1, histone h3, hydrolase
• Biological source: Thermotoga maritima; More
• Total number of polymer chains: 2
• Total formula weight: 29070.22

Authors

Cosgrove, M.S.,Wolberger, C. (deposition date: 2006-05-18, release date: 2006-11-28, Last modification date: 2019-07-24)

• Primary citation: Cosgrove, M.S.,Bever, K.,Avalos, J.L.,Muhammad, S.,Zhang, X.,Wolberger, C.; The structural basis of sirtuin substrate affinity; Biochemistry, 45:7511-7521, 2006; PubMed: 16768447; DOI: 10.1021/bi0526332

Experimental method

X-RAY DIFFRACTION (1.63 Å)