2GWS
Crystal Structure of human DNA Polymerase lambda with a G/G mismatch in the primer terminus
Summary for 2GWS
Entry DOI | 10.2210/pdb2gws/pdb |
Descriptor | 5'-D(*CP*GP*GP*CP*AP*GP*CP*GP*CP*AP*C)-3', 5'-D(*GP*TP*GP*CP*GP*G)-3', 5'-D(P*GP*CP*CP*G)-3', ... (10 entities in total) |
Functional Keywords | dna polymerase lambda, family x, mismatch extension, mutagenesis, nhej, transferase-dna complex, transferase/dna |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus : Q9UGP5 |
Total number of polymer chains | 16 |
Total formula weight | 176302.77 |
Authors | Garcia-Diaz, M.,Picher, A.J.,Bebenek, K.,Pedersen, L.C.,Kunkel, T.A.,Blanco, L. (deposition date: 2006-05-05, release date: 2006-09-05, Last modification date: 2023-08-30) |
Primary citation | Picher, A.J.,Garcia-Diaz, M.,Bebenek, K.,Pedersen, L.C.,Kunkel, T.A.,Blanco, L. Promiscuous mismatch extension by human DNA polymerase lambda. Nucleic Acids Res., 34:3259-3266, 2006 Cited by PubMed: 16807316DOI: 10.1093/nar/gkl377 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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