2GVL
Crystal Structure of Murine NMPRTase
Summary for 2GVL
Entry DOI | 10.2210/pdb2gvl/pdb |
Descriptor | Nicotinamide phosphoribosyltransferase (2 entities in total) |
Functional Keywords | visfatin, pbef, nmprtase, cancer, fk866, transferase |
Biological source | Mus musculus (house mouse) |
Cellular location | Cytoplasm: Q99KQ4 |
Total number of polymer chains | 2 |
Total formula weight | 111137.13 |
Authors | Khan, J.A.,Tao, X.,Tong, L. (deposition date: 2006-05-02, release date: 2006-07-25, Last modification date: 2011-07-13) |
Primary citation | Khan, J.A.,Tao, X.,Tong, L. Molecular basis for the inhibition of human NMPRTase, a novel target for anticancer agents. Nat.Struct.Mol.Biol., 13:582-588, 2006 Cited by PubMed: 16783377DOI: 10.1038/nsmb1105 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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