2GPP
Estrogen Related Receptor-gamma ligand binding domain complexed with a RIP140 peptide and synthetic ligand GSK4716
Summary for 2GPP
Entry DOI | 10.2210/pdb2gpp/pdb |
Related | 2GP7 2GPO 2GPU 2GPV |
Descriptor | Estrogen-related receptor gamma, Nuclear receptor-interacting protein 1, 4-HYDROXY-N'-(4-ISOPROPYLBENZYL)BENZOHYDRAZIDE, ... (4 entities in total) |
Functional Keywords | estrogen related receptor, err, errg, esrrg, nuclear receptor, steroid receptor, rip140, transcription |
Biological source | Homo sapiens (human) More |
Cellular location | Nucleus (Probable): P62508 Nucleus: P48552 |
Total number of polymer chains | 4 |
Total formula weight | 58119.68 |
Authors | Wang, L.,Zuercher, W.J.,Consler, T.G.,Lambert, M.H.,Miller, A.B.,Osband-miller, L.A.,McKee, D.D.,Willson, T.M.,Nolte, R.T. (deposition date: 2006-04-18, release date: 2006-09-26, Last modification date: 2023-08-30) |
Primary citation | Wang, L.,Zuercher, W.J.,Consler, T.G.,Lambert, M.H.,Miller, A.B.,Orband-Miller, L.A.,McKee, D.D.,Willson, T.M.,Nolte, R.T. X-ray crystal structures of the estrogen-related receptor-gamma ligand binding domain in three functional states reveal the molecular basis of small molecule regulation. J.Biol.Chem., 281:37773-37781, 2006 Cited by PubMed: 16990259DOI: 10.1074/jbc.M608410200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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