2GN9

Crystal structure of UDP-GlcNAc inverting 4,6-dehydratase in complex with NADP and UDP-Glc

Summary for 2GN9

• Entry DOI: 10.2210/pdb2gn9/pdb
• Related: 2GN4 2GN6 2GN8 2GNA
• Descriptor: UDP-GlcNAc C6 dehydratase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, URIDINE-5'-DIPHOSPHATE-GLUCOSE, ... (5 entities in total)
• Functional Keywords: rossmann fold, tyk triad, sdr, enzyme, dehydratase, udp-glcnac, nadp, lyase
• Biological source: Helicobacter pylori
• Total number of polymer chains: 2
• Total formula weight: 80264.07

Authors

Ishiyama, N.,Creuzenet, C.,Lam, J.S.,Berghuis, A.M. (deposition date: 2006-04-09, release date: 2006-05-09, Last modification date: 2023-08-30)

• Primary citation: Ishiyama, N.,Creuzenet, C.,Miller, W.L.,Demendi, M.,Anderson, E.M.,Harauz, G.,Lam, J.S.,Berghuis, A.M.; Structural Studies of FlaA1 from Helicobacter pylori Reveal the Mechanism for Inverting 4,6-Dehydratase Activity.; J.Biol.Chem., 281:24489-24495, 2006; PubMed: 16651261; DOI: 10.1074/jbc.M602393200

Experimental method

X-RAY DIFFRACTION (2.8 Å)