2GH6
Crystal structure of a HDAC-like protein with 9,9,9-trifluoro-8-oxo-N-phenylnonan amide bound
Summary for 2GH6
Entry DOI | 10.2210/pdb2gh6/pdb |
Related | 1ZZ0 1ZZ1 1ZZ3 |
Descriptor | Histone deacetylase-like amidohydrolase, ZINC ION, POTASSIUM ION, ... (5 entities in total) |
Functional Keywords | histone deacetylase, zinc-ion, trifluoromethyl ketone, hydrolase |
Biological source | Alcaligenaceae bacterium FB188 |
Total number of polymer chains | 4 |
Total formula weight | 159478.04 |
Authors | Nielsen, T.K.,Hildmann, C.,Riester, D.,Wegener, D.,Schwienhorst, A.,Ficner, R. (deposition date: 2006-03-26, release date: 2007-03-20, Last modification date: 2023-08-30) |
Primary citation | Nielsen, T.K.,Hildmann, C.,Riester, D.,Wegener, D.,Schwienhorst, A.,Ficner, R. Complex structure of a bacterial class 2 histone deacetylase homologue with a trifluoromethylketone inhibitor. Acta Crystallogr.,Sect.F, 63:270-273, 2007 Cited by PubMed: 17401192DOI: 10.1107/S1744309107012377 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.203 Å) |
Structure validation
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