2GCD
TAO2 kinase domain-staurosporine structure
Summary for 2GCD
Entry DOI | 10.2210/pdb2gcd/pdb |
Descriptor | Serine/threonine-protein kinase TAO2, STAUROSPORINE (3 entities in total) |
Functional Keywords | tao2, map3k, inhibitor, staurosporine, transferase |
Biological source | Rattus norvegicus (Norway rat) |
Cellular location | Cytoplasmic vesicle membrane ; Multi-pass membrane protein . Isoform 2: Cell projection, dendrite: Q9JLS3 |
Total number of polymer chains | 2 |
Total formula weight | 71806.15 |
Authors | Zhou, T.,Sun, L.,Gao, Y.,Earnest, S.,Cobb, M.H.,Goldsmith, E.J. (deposition date: 2006-03-14, release date: 2006-09-05, Last modification date: 2017-10-18) |
Primary citation | Zhou, T.J.,Sun, L.G.,Gao, Y.,Goldsmith, E.J. Crystal structure of the MAP3K TAO2 kinase domain bound by an inhibitor staurosporine. Acta Biochim.Biophys.Sinica, 38:385-392, 2006 Cited by PubMed: 16761096PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.55 Å) |
Structure validation
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