2G77

Crystal Structure of Gyp1 TBC domain in complex with Rab33 GTPase bound to GDP and AlF3

Summary for 2G77

• Entry DOI: 10.2210/pdb2g77/pdb
• Descriptor: GTPase-activating protein GYP1, Ras-related protein Rab-33B, MAGNESIUM ION, ... (6 entities in total)
• Functional Keywords: protein transport, gyp1 tbc domain, rab33, vesicular trafficking, hydrolase activator-protein transport complex, hydrolase activator/protein transport
• Biological source: Saccharomyces cerevisiae (baker's yeast); More
• Cellular location: Golgi apparatus, Golgi stack: Q08484; Golgi apparatus membrane; Lipid-anchor: O35963
• Total number of polymer chains: 2
• Total formula weight: 71259.11

Authors

Pan, X.,Eathiraj, S.,Munson, M.,Lambright, D.G. (deposition date: 2006-02-27, release date: 2006-07-25, Last modification date: 2021-10-20)

• Primary citation: Pan, X.,Eathiraj, S.,Munson, M.,Lambright, D.G.; TBC-domain GAPs for Rab GTPases accelerate GTP hydrolysis by a dual-finger mechanism.; Nature, 442:303-306, 2006; PubMed: 16855591; DOI: 10.1038/nature04847

Experimental method

X-RAY DIFFRACTION (2.26 Å)