2G2I
A Src-like Inactive Conformation in the Abl Tyrosine Kinase Domain
Summary for 2G2I
Entry DOI | 10.2210/pdb2g2i/pdb |
Descriptor | Abl Tyrosine Kinase, ATP-Peptide Conjugate, ADENOSINE-5'-DIPHOSPHATE (3 entities in total) |
Functional Keywords | protein kinase, transferase |
Biological source | Homo sapiens (human) More |
Cellular location | Cytoplasm, cytoskeleton. Isoform IB: Nucleus membrane; Lipid-anchor: P00519 |
Total number of polymer chains | 4 |
Total formula weight | 70275.63 |
Authors | Levinson, N.M.,Kuchment, O. (deposition date: 2006-02-16, release date: 2006-05-23, Last modification date: 2023-08-30) |
Primary citation | Levinson, N.M.,Kuchment, O.,Shen, K.,Young, M.A.,Koldobskiy, M.,Karplus, M.,Cole, P.A.,Kuriyan, J. A SRC-like inactive conformation in the abl tyrosine kinase domain. Plos Biol., 4:753-767, 2006 Cited by PubMed: 16640460DOI: 10.1371/journal.pbio.0040144 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.12 Å) |
Structure validation
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