2FTL

Crystal structure of trypsin complexed with BPTI at 100K

Summary for 2FTL

Entry DOI	10.2210/pdb2ftl/pdb
Related	2FTM 2PTC
Descriptor	Cationic trypsin, Pancreatic trypsin inhibitor, SODIUM ION, ... (7 entities in total)
Functional Keywords	protease-inhibitor complex, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological source	Bos taurus (cattle) More
Cellular location	Secreted, extracellular space: P00760 Secreted: P00974
Total number of polymer chains	2
Total formula weight	31096.90
Authors	Hanson, W.M.,Horvath, M.P.,Goldenberg, D.P. (deposition date: 2006-01-24, release date: 2006-02-14, Last modification date: 2023-08-30)
Primary citation	Hanson, W.M.,Domek, G.J.,Horvath, M.P.,Goldenberg, D.P. Rigidification of a Flexible Protease Inhibitor Variant upon Binding to Trypsin. J.Mol.Biol., 366:230-243, 2007 Cited by PubMed: 17157870 DOI: 10.1016/j.jmb.2006.11.003 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.62 Å)

Structure validation