2FRA
Human Cathepsin S with CRA-27934, a Nitrile Inhibitor
Summary for 2FRA
Entry DOI | 10.2210/pdb2fra/pdb |
Descriptor | cathepsin S, N-[1-(AMINOMETHYL)CYCLOPROPYL]-3-(BENZYLSULFONYL)-N~2~-[(1S)-2,2,2-TRIFLUORO-1-(4-HYDROXYPHENYL)ETHYL]-L-ALANINAMIDE (3 entities in total) |
Functional Keywords | papain, cysteine protease, drug design, 27934, hydrolase |
Biological source | Homo sapiens (human) |
Cellular location | Lysosome: P25774 |
Total number of polymer chains | 2 |
Total formula weight | 50983.09 |
Authors | Somoza, J.R. (deposition date: 2006-01-19, release date: 2006-07-25, Last modification date: 2017-10-18) |
Primary citation | Somoza, J.R. Human Cathepsin S with CRA-27934, a Nitrile Inhibitor To be Published, |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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