2FQ6
Cystathionine beta-lyase (cbl) from escherichia coli in complex with n-hydrazinocarbonylmethyl-2-trifluoromethyl-benzamide
Summary for 2FQ6
Entry DOI | 10.2210/pdb2fq6/pdb |
Descriptor | Cystathionine beta-lyase, PHOSPHORIC ACID MONO-(5-HYDROXY-6-METHYL-4-{[2-(2-TRIFLUOROMETHYL-BENZOYLAMINO)-ACETYL]-HYDRAZONOMETHYL}-PYRIDIN-3-YLMETHYL)ESTER (3 entities in total) |
Functional Keywords | protein-inhibitor complex, plp cofactor covalently bound to p3f inhibitor, lyase |
Biological source | Escherichia coli |
Cellular location | Cytoplasm: P06721 |
Total number of polymer chains | 2 |
Total formula weight | 91845.91 |
Authors | Junop, M.S. (deposition date: 2006-01-17, release date: 2006-12-26, Last modification date: 2023-08-30) |
Primary citation | Ejim, L.J.,Blanchard, J.E.,Koteva, K.P.,Sumerfield, R.,Elowe, N.H.,Chechetto, J.D.,Brown, E.D.,Junop, M.S.,Wright, G.D. Inhibitors of bacterial cystathionine beta-lyase: leads for new antimicrobial agents and probes of enzyme structure and function. J.Med.Chem., 50:755-764, 2007 Cited by PubMed: 17300162DOI: 10.1021/jm061132r PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.78 Å) |
Structure validation
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