2FOU
Human Carbonic Anhydrase II complexed with two-prong inhibitors
Summary for 2FOU
| Entry DOI | 10.2210/pdb2fou/pdb |
| Related | 2FOV 2FOY 2cba 2foq 2fos |
| Descriptor | Carbonic Anhydrase II, ZINC ION, COPPER (II) ION, ... (6 entities in total) |
| Functional Keywords | lyase, inhibitor |
| Biological source | Homo sapiens (human) |
| Cellular location | Cytoplasm: P00918 |
| Total number of polymer chains | 1 |
| Total formula weight | 30832.79 |
| Authors | Jude, K.M.,Christianson, D.W. (deposition date: 2006-01-14, release date: 2006-04-04, Last modification date: 2023-08-30) |
| Primary citation | Jude, K.M.,Banerjee, A.L.,Haldar, M.K.,Manokaran, S.,Roy, B.,Mallik, S.,Srivastava, D.K.,Christianson, D.W. Ultrahigh resolution crystal structures of human carbonic anhydrases I and II complexed with two-prong inhibitors reveal the molecular basis of high affinity. J.Am.Chem.Soc., 128:3011-3018, 2006 Cited by PubMed: 16506782DOI: 10.1021/ja057257n PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (0.99 Å) |
Structure validation
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