2F9O

Crystal Structure of the Recombinant Human Alpha I Tryptase Mutant D216G

Summary for 2F9O

Entry DOI	10.2210/pdb2f9o/pdb
Related	2F9N 2F9P
Descriptor	Tryptase alpha-1, alpha-L-fucopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)]2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total)
Functional Keywords	serine proteinase, trypsin-like, difucosylation, hydrolase
Biological source	Homo sapiens (human)
Total number of polymer chains	4
Total formula weight	111783.85
Authors	Rohr, K.B.,Selwood, T.,Marquardt, U.,Huber, R.,Schechter, N.M.,Bode, W.,Than, M.E. (deposition date: 2005-12-06, release date: 2006-01-31, Last modification date: 2023-08-30)
Primary citation	Rohr, K.B.,Selwood, T.,Marquardt, U.,Huber, R.,Schechter, N.M.,Bode, W.,Than, M.E. X-ray Structures of Free and Leupeptin-complexed Human alpha I-Tryptase Mutants: Indication for an alpha to beta-Tryptase Transition J.Mol.Biol., 357:195-209, 2005 Cited by PubMed: 16414069 DOI: 10.1016/j.jmb.2005.12.037 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation