2F7P

Golgi alpha-mannosidase II complex with benzyl-mannostatin A

Summary for 2F7P

Entry DOI	10.2210/pdb2f7p/pdb
Related	1HTY 1HWW 1HXK 1PS3 1QWN 1QWU 1QX1 2F7O 2F7Q 2F7R
Descriptor	alpha-mannosidase II, 2-acetamido-2-deoxy-beta-D-glucopyranose, ZINC ION, ... (6 entities in total)
Functional Keywords	glycosyl hydrolase family 38, hydrolase
Biological source	Drosophila melanogaster (fruit fly)
Total number of polymer chains	1
Total formula weight	120375.77
Authors	Kuntz, D.A.,Rose, D.R. (deposition date: 2005-12-01, release date: 2006-07-04, Last modification date: 2023-08-23)
Primary citation	Kawatkar, S.P.,Kuntz, D.A.,Woods, R.J.,Rose, D.R.,Boons, G.J. Structural Basis of the Inhibition of Golgi alpha-Mannosidase II by Mannostatin A and the Role of the Thiomethyl Moiety in Ligand-Protein Interactions. J.Am.Chem.Soc., 128:8310-8319, 2006 Cited by PubMed: 16787095 DOI: 10.1021/ja061216p PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.28 Å)

Structure validation