2E9W
Crystal structure of the extracellular domain of Kit in complex with stem cell factor (SCF)
Summary for 2E9W
Entry DOI | 10.2210/pdb2e9w/pdb |
Related | 1EXZ 2EC8 |
Descriptor | Mast/stem cell growth factor receptor, Kit ligand, 2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total) |
Functional Keywords | glycoprotein, receptor tyrosine kinase, growth factor cytokine, dimerization, transferase-hormone complex, transferase/hormone |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 4 |
Total formula weight | 143235.13 |
Authors | Yuzawa, S.,Opatowsky, Y.,Zhang, Z.,Mandiyan, V.,Lax, I.,Schlessinger, J. (deposition date: 2007-01-27, release date: 2007-08-07, Last modification date: 2023-10-25) |
Primary citation | Yuzawa, S.,Opatowsky, Y.,Zhang, Z.,Mandiyan, V.,Lax, I.,Schlessinger, J. Structural Basis for Activation of the Receptor Tyrosine Kinase KIT by Stem Cell Factor Cell(Cambridge,Mass.), 130:323-334, 2007 Cited by PubMed: 17662946DOI: 10.1016/j.cell.2007.05.055 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.5 Å) |
Structure validation
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