2E9C

E. coli undecaprenyl pyrophosphate synthase in complex with BPH-675

Summary for 2E9C

Entry DOI	10.2210/pdb2e9c/pdb
Related	1X06 1X07 1X08 1X09 2E98 2E99 2E9A 2E9D
Descriptor	Undecaprenyl pyrophosphate synthetase, 1-HYDROXY-2-[3'-(NAPHTHALENE-2-SULFONYLAMINO)-BIPHENYL-3-YL]ETHYLIDENE-1,1-BISPHOSPHONIC ACID (3 entities in total)
Functional Keywords	cell wall, prenyltransferase, farnesyl pyrophosphate, bisphosphonate, antibiotic, transferase
Biological source	Escherichia coli
Total number of polymer chains	2
Total formula weight	59216.07
Authors	Guo, R.T.,Ko, T.P.,Cao, R.,Liang, P.H.,Oldfield, E.,Wang, A.H.J. (deposition date: 2007-01-24, release date: 2007-06-12, Last modification date: 2023-10-25)
Primary citation	Guo, R.T.,Cao, R.,Liang, P.H.,Ko, T.P.,Chang, T.H.,Hudock, M.P.,Jeng, W.Y.,Chen, C.K.M.,Zhang, Y.,Song, Y.,Kuo, C.J.,Yin, F.,Oldfield, E.,Wang, A.H.J. Bisphosphonates target multiple sites in both cis- and trans-prenyltransferases Proc.Natl.Acad.Sci.Usa, 104:10022-10027, 2007 Cited by PubMed: 17535895 DOI: 10.1073/pnas.0702254104 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.05 Å)

Structure validation