2DTU

Crystal structure of the beta hairpin loop deletion variant of RB69 gp43 in complex with DNA containing an abasic site analog

Summary for 2DTU

• Entry DOI: 10.2210/pdb2dtu/pdb
• Related: 1CLQ 1IG9 1Q9X 1Q9Y 1RV2
• Descriptor: 5'-D(*CP*GP*(3DR)P*CP*TP*TP*AP*TP*GP*AP*CP*AP*GP*CP*CP*GP*CP*G)-3', 5'-D(*GP*CP*GP*GP*CP*TP*GP*TP*CP*AP*TP*AP*AP*GP*A)-3', DNA polymerase, ... (4 entities in total)
• Functional Keywords: dna polymerase, abasic site, dna lesion, beta hairpin deletion, transferase-dna complex, transferase/dna
• Biological source: Enterobacteria phage RB69
• Total number of polymer chains: 12
• Total formula weight: 455050.45

Authors

Aller, P.,Hogg, M.,Konigsberg, W.,Wallace, S.S.,Doublie, S. (deposition date: 2006-07-15, release date: 2006-12-05, Last modification date: 2023-10-25)

• Primary citation: Hogg, M.,Aller, P.,Konigsberg, W.,Wallace, S.S.,Doublie, S.; Structural and biochemical investigation of the role in proofreading of a beta hairpin loop found in the exonuclease domain of a replicative DNA polymerase of the B family.; J.Biol.Chem., 282:1432-1444, 2007; PubMed: 17098747; DOI: 10.1074/jbc.M605675200

Experimental method

X-RAY DIFFRACTION (2.37 Å)