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2DPJ

structure of hPoli with DNA and dTTP

Summary for 2DPJ
Entry DOI10.2210/pdb2dpj/pdb
Related1T3N 2ALZ 2DPI
Descriptor5'-D(*AP*GP*GP*AP*CP*CP*(DOC))-3', 5'-D(*TP*(EDA)P*GP*GP*GP*TP*CP*CP*T)-3', DNA polymerase iota, ... (6 entities in total)
Functional Keywordsdna dependent dna polymerase, ethenoda adduct, lesion bypass, dttp, transferase-dna complex, transferase/dna
Biological sourceHomo sapiens (human)
Cellular locationNucleus: Q9UNA4
Total number of polymer chains3
Total formula weight52420.37
Authors
Nair, D.T.,Johnson, R.E.,Prakash, L.,Prakash, S.,Aggarwal, A.K. (deposition date: 2006-05-12, release date: 2006-07-04, Last modification date: 2023-10-25)
Primary citationNair, D.T.,Johnson, R.E.,Prakash, L.,Prakash, S.,Aggarwal, A.K.
Hoogsteen base pair formation promotes synthesis opposite the 1,N(6)-ethenodeoxyadenosine lesion by human DNA polymerase iota.
Nat.Struct.Mol.Biol., 13:619-625, 2006
Cited by
PubMed: 16819516
DOI: 10.1038/nsmb1118
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.3 Å)
Structure validation

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