1T3N
Structure of the catalytic core of DNA polymerase Iota in complex with DNA and dTTP
Summary for 1T3N
Entry DOI | 10.2210/pdb1t3n/pdb |
Descriptor | Template DNA strand, Primer DNA strand, polymerase (DNA directed) iota, ... (6 entities in total) |
Functional Keywords | protein, dna, dttp, replication-dna complex, replication/dna |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus : Q9UNA4 |
Total number of polymer chains | 4 |
Total formula weight | 96507.63 |
Authors | Nair, D.T.,Johnson, R.E.,Prakash, S.,Prakash, L.,Aggarwal, A.K. (deposition date: 2004-04-27, release date: 2004-07-20, Last modification date: 2018-04-18) |
Primary citation | Nair, D.T.,Johnson, R.E.,Prakash, S.,Prakash, L.,Aggarwal, A.K. Replication by human DNA polymerase-iota occurs by Hoogsteen base-pairing. Nature, 430:377-380, 2004 Cited by PubMed: 15254543DOI: 10.1038/nature02692 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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