2CJS
Structural Basis for a Munc13-1 Homodimer - Munc13-1 - RIM Heterodimer Switch: C2-domains as Versatile Protein-Protein Interaction Modules
Summary for 2CJS
Entry DOI | 10.2210/pdb2cjs/pdb |
Related | 1Y8F 2A20 2BWQ 2CJT |
Descriptor | UNC-13 HOMOLOG A, REGULATING SYNAPTIC MEMBRANE EXOCYTOSIS PROTEIN 2, 1,2-ETHANEDIOL, ... (6 entities in total) |
Functional Keywords | neurotransmitter transport, exocytosis, zinc finger, synaptosome, phorbol-ester binding, neurotransmitter release, metal-binding, protein- protein interactions, rim, munc13, synapse, transport, c2 domains |
Biological source | RATTUS NORVEGICUS (RAT) More |
Total number of polymer chains | 3 |
Total formula weight | 45004.69 |
Authors | Lu, J.,Machius, M.,Dulubova, I.,Dai, H.,Sudhof, T.C.,Tomchick, D.R.,Rizo, J. (deposition date: 2006-04-06, release date: 2006-06-07, Last modification date: 2024-05-08) |
Primary citation | Lu, J.,Machius, M.,Dulubova, I.,Dai, H.,Sudhof, T.C.,Tomchick, D.R.,Rizo, J. Structural Basis for a Munc13-1 Homodimer to Munc13-1/Rim Heterodimer Switch. Plos Biol., 4:E192-, 2006 Cited by PubMed: 16732694DOI: 10.1371/JOURNAL.PBIO.0040192 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.78 Å) |
Structure validation
Download full validation report