2CG5

Structure of aminoadipate-semialdehyde dehydrogenase- phosphopantetheinyl transferase in complex with cytosolic acyl carrier protein and coenzyme A

Summary for 2CG5

• Entry DOI: 10.2210/pdb2cg5/pdb
• Related: 2BYD 2C43
• Descriptor: L-AMINOADIPATE-SEMIALDEHYDE DEHYDROGENASE-PHOSPHOPANTETHEINYL TRANSFERASE, FATTY ACID SYNTHASE, COENZYME A, ... (7 entities in total)
• Functional Keywords: transferase-hydrolase complex, transferase-hydrolase (complex), fatty acid biosynthesis, phosphopantetheine transferase, fasn, acp, coenzyme a, transferase, hydrolase, lipid synthesis, lyase, complex, transferase/hydrolase
• Biological source: HOMO SAPIENS (HUMAN); More
• Cellular location: Cytoplasm : Q9NRN7 P49327
• Total number of polymer chains: 2
• Total formula weight: 48087.11

Authors

Bunkoczi, G.,Joshi, A.,Papagrigoriu, E.,Arrowsmith, C.,Edwards, A.,Sundstrom, M.,Weigelt, J.,von Delft, F.,Smith, S.,Oppermann, U. (deposition date: 2006-02-27, release date: 2006-03-01, Last modification date: 2023-12-13)

• Primary citation: Bunkoczi, G.,Pasta, S.,Joshi, A.,Wu, X.,Kavanagh, K.L.,Smith, S.,Oppermann, U.; Mechanism and Substrate Recognition of Human Holo Acp Synthase.; Chem.Biol., 14:1243-, 2007; PubMed: 18022563; DOI: 10.1016/J.CHEMBIOL.2007.10.013

Experimental method

X-RAY DIFFRACTION (2.7 Å)