2C92
LUMAZINE SYNTHASE FROM MYCOBACTERIUM TUBERCULOSIS BOUND TO 3-(1,3,7- TRIHYDRO-9-D-RIBITYL-2,6,8-PURINETRIONE-7-YL) PENTANE 1 PHOSPHATE
Summary for 2C92
Entry DOI | 10.2210/pdb2c92/pdb |
Related | 1W19 1W29 2C92 2C94 2C97 2C9B 2C9D |
Descriptor | 6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE, 3-(1,3,7-TRIHYDRO-9-D-RIBITYL-2,6,8-PURINETRIONE-7-YL) 1-PHOSPHATE, POTASSIUM ION, ... (6 entities in total) |
Functional Keywords | transferase, riboflavin biosynthesis, mycobacterium tuberculosis, lumazine synthase, inhibitor binding |
Biological source | MYCOBACTERIUM TUBERCULOSIS |
Total number of polymer chains | 5 |
Total formula weight | 85214.51 |
Authors | Morgunova, E.,Illarionov, B.,Jin, G.,Haase, I.,Fischer, M.,Cushman, M.,Bacher, A.,Ladenstein, R. (deposition date: 2005-12-09, release date: 2006-12-13, Last modification date: 2023-12-13) |
Primary citation | Morgunova, E.,Illarionov, B.,Sambaiah, T.,Haase, I.,Bacher, A.,Cushman, M.,Fischer, M.,Ladenstein, R. Structural and Thermodynamic Insights Into the Binding Mode of Five Novel Inhibitors of Lumazine Synthase from Mycobacterium Tuberculosis. FEBS J., 273:4790-, 2006 Cited by PubMed: 16984393DOI: 10.1111/J.1742-4658.2006.05481.X PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.6 Å) |
Structure validation
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