2BHK

Crystal structure of human growth and differentiation factor 5 (GDF5)

Summary for 2BHK

• Entry DOI: 10.2210/pdb2bhk/pdb
• Related: 1WAQ
• Descriptor: GROWTH DIFFERENTIATION FACTOR 5, ISOPROPYL ALCOHOL (3 entities in total)
• Functional Keywords: growth factor, growth differentiation factor, bone morphogenetic factor, hormone-receptor interaction, cystine knot, preformed receptor dimer, cytokine, dwarfism, glycoprotein
• Biological source: HOMO SAPIENS (HUMAN)
• Total number of polymer chains: 1
• Total formula weight: 13899.11

Authors

Schreuder, H.,Liesum, A.,Pohl, J.,Kruse, M.,Koyama, M. (deposition date: 2005-01-12, release date: 2005-03-11, Last modification date: 2023-12-13)

• Primary citation: Schreuder, H.,Liesum, A.,Pohl, J.,Kruse, M.,Koyama, M.; Crystal Structure of Recombinant Human Growth Differentiation Factor 5. Evidence for Interaction of the Type I and Type II Receptor Binding Sites.; Biochem.Biophys.Res.Commun., 329:1076-, 2005; PubMed: 15752764; DOI: 10.1016/J.BBRC.2005.02.078

Experimental method

X-RAY DIFFRACTION (2.4 Å)