2B23

Human estrogen receptor alpha ligand-binding domain and a glucocorticoid receptor-interacting protein 1 NR box II peptide

Summary for 2B23

Entry DOI	10.2210/pdb2b23/pdb
Related	2B1V 2B1Z
Descriptor	Estrogen receptor, Nuclear receptor coactivator 2 (3 entities in total)
Functional Keywords	estrogen receptor, lbd, grip peptide, hormone-growth factor receptor complex, hormone/growth factor receptor
Biological source	Homo sapiens (human) More
Total number of polymer chains	4
Total formula weight	62215.51
Authors	Rajan, S.S.,Hsieh, R.W.,Sharma, S.K.,Greene, G.L. (deposition date: 2005-09-16, release date: 2006-09-19, Last modification date: 2023-08-23)
Primary citation	Nettles, K.W.,Bruning, J.B.,Gil, G.,Nowak, J.,Sharma, S.K.,Hahm, J.B.,Kulp, K.,Hochberg, R.B.,Zhou, H.,Katzenellenbogen, J.A.,Katzenellenbogen, B.S.,Kim, Y.,Joachmiak, A.,Greene, G.L. NFkappaB selectivity of estrogen receptor ligands revealed by comparative crystallographic analyses Nat.Chem.Biol., 4:241-247, 2008 Cited by PubMed: 18344977 DOI: 10.1038/nchembio.76 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation