2B1P
inhibitor complex of JNK3
Summary for 2B1P
Entry DOI | 10.2210/pdb2b1p/pdb |
Descriptor | Mitogen-activated protein kinase 10, SULFATE ION, 3-{6-[(2-CHLOROPHENYL)AMINO]-1H-INDAZOL-3-YL}-5-{[4-(DIMETHYLAMINO)BUTANOYL]AMINO}BENZOIC ACID, ... (5 entities in total) |
Functional Keywords | enzyme-inhibitor complex, kinase inhibitor, transferase |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: P53779 |
Total number of polymer chains | 1 |
Total formula weight | 41731.72 |
Authors | Swahn, B.M.,Huerta, F.,Kallin, E.,Malmstrom, J.,Weigelt, T.,Viklund, J.,Womack, P.,Xue, Y.,Ohberg, L. (deposition date: 2005-09-16, release date: 2006-09-16, Last modification date: 2024-03-13) |
Primary citation | Swahn, B.M.,Huerta, F.,Kallin, E.,Malmstrom, J.,Weigelt, T.,Viklund, J.,Womack, P.,Xue, Y.,Ohberg, L. Design and synthesis of 6-anilinoindazoles as selective inhibitors of c-Jun N-terminal kinase-3 Bioorg.Med.Chem.Lett., 15:5095-5099, 2005 Cited by PubMed: 16140012DOI: 10.1016/j.bmcl.2005.06.083 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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