2B0F

NMR Structure of the Human Rhinovirus 3C Protease (serotype 14) with covalently bound Ace-LEALFQ-ethylpropionate inhibitor

Summary for 2B0F

• Entry DOI: 10.2210/pdb2b0f/pdb
• Related: 1CQQ 1L1N
• Related PRD ID: PRD_000363
• Descriptor: Protease 3C, Ace-LEALFQ-ethylpropionate (2 entities in total)
• Functional Keywords: beta barrel, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: rhinovirus B14; More
• Cellular location: Protein VP2: Virion. Protein VP3: Virion. Protein VP1: Virion. Protein 2B: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 2C: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 3A: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 3B: Virion (Potential). Picornain 3C: Host cytoplasm (Potential). RNA-directed RNA polymerase 3D-POL: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential): P03303
• Total number of polymer chains: 2
• Total formula weight: 20823.85

Authors

Bjorndahl, T.C.,Andrew, L.C.,Wishart, D.S. (deposition date: 2005-09-13, release date: 2006-09-05, Last modification date: 2023-11-15)

• Primary citation: Bjorndahl, T.C.,Andrew, L.C.,Semenchenko, V.,Wishart, D.S.; NMR solution structures of the apo and peptide-inhibited human rhinovirus 3C protease (Serotype 14): structural and dynamic comparison; Biochemistry, 46:12945-12958, 2007; PubMed: 17944485; DOI: 10.1021/bi7010866

Experimental method

SOLUTION NMR