2AQ8

Crystal structure of wild-type of Enoyl-ACP(CoA) reductase from Mycobacterium tuberculosis in complex with NADH.

Summary for 2AQ8

Entry DOI	10.2210/pdb2aq8/pdb
Related	1ENY
Descriptor	Enoyl-Acyl-carrier-protein reductase, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, LYSINE, ... (4 entities in total)
Functional Keywords	enoyl-acyl carrier protein, oxidoreductase
Biological source	Mycobacterium tuberculosis
Total number of polymer chains	1
Total formula weight	29367.42
Authors	Oliveira, J.S.,Pereira, J.H.,Rodrigues, N.C.,Canduri, F.,Basso, L.A.,de Azevedo Jr., W.F.,Santos, D.S. (deposition date: 2005-08-17, release date: 2006-05-23, Last modification date: 2023-08-23)
Primary citation	Oliveira, J.S.,Pereira, J.H.,Canduri, F.,Rodrigues, N.C.,de Souza, O.N.,de Azevedo Jr., W.F.,Basso, L.A.,Santos, D.S. Crystallographic and Pre-steady-state Kinetics Studies on Binding of NADH to Wild-type and Isoniazid-resistant Enoyl-ACP(CoA) Reductase Enzymes from Mycobacterium tuberculosis. J.Mol.Biol., 359:646-666, 2006 Cited by PubMed: 16647717 DOI: 10.1016/j.jmb.2006.03.055 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.92 Å)

Structure validation