2ANW
Expression, crystallization and three-dimensional structure of the catalytic domain of human plasma kallikrein: Implications for structure-based design of protease inhibitors
Summary for 2ANW
Entry DOI | 10.2210/pdb2anw/pdb |
Related | 2ANY |
Descriptor | plasma kallikrein, light chain, BENZAMIDINE (3 entities in total) |
Functional Keywords | trypsin-like serine protease; enzymatically deglycosylated, blood clotting, hydrolase |
Biological source | Homo sapiens (human) |
Cellular location | Secreted: P03952 |
Total number of polymer chains | 1 |
Total formula weight | 27219.96 |
Authors | Tang, J.,Yu, C.L.,Williams, S.R.,Springman, E.,Jeffery, D.,Sprengeler, P.A.,Estevez, A.,Sampang, J.,Shrader, W.,Spencer, J.R.,Young, W.B.,McGrath, M.E.,Katz, B.A. (deposition date: 2005-08-11, release date: 2005-10-11, Last modification date: 2023-08-23) |
Primary citation | Tang, J.,Yu, C.L.,Williams, S.R.,Springman, E.,Jeffery, D.,Sprengeler, P.A.,Estevez, A.,Sampang, J.,Shrader, W.,Spencer, J.,Young, W.,McGrath, M.,Katz, B.A. Expression, crystallization, and three-dimensional structure of the catalytic domain of human plasma kallikrein. J.Biol.Chem., 280:41077-41089, 2005 Cited by PubMed: 16199530DOI: 10.1074/jbc.M506766200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.85 Å) |
Structure validation
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