2AK5
beta PIX-SH3 complexed with a Cbl-b peptide
Summary for 2AK5
Entry DOI | 10.2210/pdb2ak5/pdb |
Descriptor | Rho guanine nucleotide exchange factor 7, 8-residue peptide from a signal transduction protein CBL-B (3 entities in total) |
Functional Keywords | adaptor proteins, cin85, pix/cool, cbl, protein-protein interaction, endocytosis, endocytosis-exocytosis complex, endocytosis/exocytosis |
Biological source | Rattus norvegicus (Norway rat) More |
Cellular location | Cytoplasm: Q13191 |
Total number of polymer chains | 3 |
Total formula weight | 15589.09 |
Authors | Jozic, D.,Cardenes, N.,Deribe, Y.L.,Moncalian, G.,Hoeller, D.,Groemping, Y.,Dikic, I.,Rittinger, K.,Bravo, J. (deposition date: 2005-08-03, release date: 2005-10-11, Last modification date: 2023-08-23) |
Primary citation | Jozic, D.,Cardenes, N.,Deribe, Y.L.,Moncalian, G.,Hoeller, D.,Groemping, Y.,Dikic, I.,Rittinger, K.,Bravo, J. Cbl promotes clustering of endocytic adaptor proteins. Nat.Struct.Mol.Biol., 12:972-979, 2005 Cited by PubMed: 16228008DOI: 10.1038/nsmb1000 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.85 Å) |
Structure validation
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