2A6E
Crystal structure of the T. Thermophilus RNA polymerase holoenzyme
Summary for 2A6E
Entry DOI | 10.2210/pdb2a6e/pdb |
Related | 1IW7 1SMY 2A68 2A69 2a6h |
Descriptor | DNA-directed RNA polymerase alpha chain, DNA-directed RNA polymerase beta chain, DNA-directed RNA polymerase beta' chain, ... (8 entities in total) |
Functional Keywords | rna polymerase holoenzyme, bridge helix, transcription regulation, riken structural genomics/proteomics initiative, rsgi, structural genomics, transferase |
Biological source | Thermus thermophilus More |
Cellular location | Cytoplasm : Q5SKW1 |
Total number of polymer chains | 12 |
Total formula weight | 853581.22 |
Authors | Artsimovitch, I.,Vassylyeva, M.N.,Svetlov, D.,Svetlov, V.,Perederina, A.,Igarashi, N.,Matsugaki, N.,Wakatsuki, S.,Tahirov, T.H.,Vassylyev, D.G.,RIKEN Structural Genomics/Proteomics Initiative (RSGI) (deposition date: 2005-07-02, release date: 2005-09-20, Last modification date: 2023-08-23) |
Primary citation | Artsimovitch, I.,Vassylyeva, M.N.,Svetlov, D.,Svetlov, V.,Perederina, A.,Igarashi, N.,Matsugaki, N.,Wakatsuki, S.,Tahirov, T.H.,Vassylyev, D.G. Allosteric modulation of the RNA polymerase catalytic reaction is an essential component of transcription control by rifamycins. Cell(Cambridge,Mass.), 122:351-363, 2005 Cited by PubMed: 16096056DOI: 10.1016/j.cell.2005.07.014 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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