2A3X
Decameric crystal structure of human serum amyloid P-component bound to Bis-1,2-{[(Z)-2carboxy- 2-methyl-1,3-dioxane]- 5-yloxycarbonyl}-piperazine
Summary for 2A3X
Entry DOI | 10.2210/pdb2a3x/pdb |
Related | 1LGN |
Descriptor | Serum amyloid P-component, CALCIUM ION, BIS-1,2-{[(Z)-2CARBOXY-2-METHYL-1,3-DIOXANE]-5-YLOXYCARBONYL}-PIPERAZINE (3 entities in total) |
Functional Keywords | multivalent ligand, serum amyloid, metal binding protein |
Biological source | Homo sapiens (human) |
Cellular location | Secreted: P02743 |
Total number of polymer chains | 10 |
Total formula weight | 235013.33 |
Authors | Ho, J.G.,Kitov, P.I.,Paszkiewicz, E.,Sadowska, J.,Bundle, D.R.,Ng, K.K. (deposition date: 2005-06-27, release date: 2005-07-26, Last modification date: 2023-08-23) |
Primary citation | Ho, J.G.,Kitov, P.I.,Paszkiewicz, E.,Sadowska, J.,Bundle, D.R.,Ng, K.K. Ligand-assisted Aggregation of Proteins: DIMERIZATION OF SERUM AMYLOID P COMPONENT BY BIVALENT LIGANDS. J.Biol.Chem., 280:31999-32008, 2005 Cited by PubMed: 16036920DOI: 10.1074/jbc.M504403200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
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