1ZXN

Human DNA topoisomerase IIa ATPase/ADP

Summary for 1ZXN

• Entry DOI: 10.2210/pdb1zxn/pdb
• Related: 1ZXM
• Descriptor: DNA topoisomerase II, alpha isozyme, MAGNESIUM ION, ADENOSINE-5'-DIPHOSPHATE, ... (6 entities in total)
• Functional Keywords: ghkl nucleotide-binding fold, isomerase
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm: P11388
• Total number of polymer chains: 4
• Total formula weight: 184732.38

Authors

Wei, H.,Ruthenburg, A.J.,Bechis, S.K.,Verdine, G.L. (deposition date: 2005-06-08, release date: 2005-08-23, Last modification date: 2024-02-14)

• Primary citation: Wei, H.,Ruthenburg, A.J.,Bechis, S.K.,Verdine, G.L.; Nucleotide-dependent Domain Movement in the ATPase Domain of a Human Type IIA DNA Topoisomerase.; J.Biol.Chem., 280:37041-37047, 2005; PubMed: 16100112; DOI: 10.1074/jbc.M506520200

Experimental method

X-RAY DIFFRACTION (2.51 Å)