1ZLH

Crystal structure of the tick carboxypeptidase inhibitor in complex with bovine carboxypeptidase A

Summary for 1ZLH

• Entry DOI: 10.2210/pdb1zlh/pdb
• Related: 1ZLI
• Descriptor: Carboxypeptidase A1, carboxypeptidase inhibitor, ZINC ION, ... (4 entities in total)
• Functional Keywords: inhibitor-metallocarboxypeptidase complex, beta-defensin fold (tci), eight-stranded twisted beta-sheet surrounded by eight alpha-helices (cpa), hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Bos taurus (cattle); More
• Cellular location: Secreted, extracellular space: P00730
• Total number of polymer chains: 2
• Total formula weight: 42993.90

Authors

Arolas, J.L.,Popowicz, G.M.,Lorenzo, J.,Sommerhoff, C.P.,Huber, R.,Aviles, F.X.,Holak, T.A. (deposition date: 2005-05-06, release date: 2005-07-05, Last modification date: 2017-10-11)

• Primary citation: Arolas, J.L.,Popowicz, G.M.,Lorenzo, J.,Sommerhoff, C.P.,Huber, R.,Aviles, F.X.,Holak, T.A.; The Three-Dimensional Structures of Tick Carboxypeptidase Inhibitor in Complex with A/B Carboxypeptidases Reveal a Novel Double-headed Binding Mode; J.Mol.Biol., 350:489-498, 2005; PubMed: 15961103; DOI: 10.1016/j.jmb.2005.05.015

Experimental method

X-RAY DIFFRACTION (1.7 Å)