1ZH9
carbonic anhydrase II in complex with N-4-Methyl-1-piperazinyl-N'-(p-sulfonamide)phenylthiourea as sulfonamide inhibitor
Summary for 1ZH9
Entry DOI | 10.2210/pdb1zh9/pdb |
Related | 1OQ5 1Z9Y 1ZFQ |
Descriptor | Carbonic anhydrase II, ZINC ION, 4-({[(4-METHYLPIPERAZIN-1-YL)AMINO]CARBONOTHIOYL}AMINO)BENZENESULFONAMIDE, ... (5 entities in total) |
Functional Keywords | 10 stranded, twisted beta-sheets, lyase |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm : P00918 |
Total number of polymer chains | 1 |
Total formula weight | 29909.87 |
Authors | Honndorf, V.S.,Heine, A.,Klebe, G.,Supuran, C.T. (deposition date: 2005-04-23, release date: 2006-05-23, Last modification date: 2024-03-13) |
Primary citation | Honndorf, V.S.,Heine, A.,Klebe, G.,Supuran, C.T. carbonic anhydrase II in complex with N-4-Methyl-1-piperazinyl-N'-(p-sulfonamide)phenylthiourea as sulfonamide inhibitor To be Published, |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
Download full validation report