1ZFX

The Structure of a minimal all-RNA Hairpin Ribozyme with the mutant G8U at the cleavage site

Summary for 1ZFX

• Entry DOI: 10.2210/pdb1zfx/pdb
• Related: 1X9C 1X9K 1ZFR 1ZFT 1ZFV
• Descriptor: 5'-R(*UP*CP*CP*CP*AP*GP*UP*CP*CP*AP*CP*CP*G)-3', 5'-R(*CP*GP*GP*UP*GP*AP*UP*AP*AP*GP*GP*G)-3', 5'-R(*GP*GP*CP*AP*GP*AP*GP*AP*AP*AP*CP*AP*CP*AP*CP*GP*A)-3', ... (7 entities in total)
• Functional Keywords: hairpin ribozyme, all-rna, cobalt hexaamine, mutation, low salt, s-turn, e-loop, ribose zipper, catalytic rna, rna
• Total number of polymer chains: 4
• Total formula weight: 19929.19

Authors

Wedekind, J.E. (deposition date: 2005-04-20, release date: 2006-02-14, Last modification date: 2023-08-23)

• Primary citation: Salter, J.,Krucinska, J.,Alam, S.,Grum-Tokars, V.,Wedekind, J.E.; Water in the Active Site of an All-RNA Hairpin Ribozyme and Effects of Gua8 Base Variants on the Geometry of Phosphoryl Transfer.; Biochemistry, 45:686-700, 2006; PubMed: 16411744; DOI: 10.1021/bi051887k

Experimental method

X-RAY DIFFRACTION (2.38 Å)