1YOL
Crystal structure of Src kinase domain in complex with CGP77675
Summary for 1YOL
Entry DOI | 10.2210/pdb1yol/pdb |
Related | 1YOJ 1YOM |
Descriptor | Proto-oncogene tyrosine-protein kinase Src, 1-{4-[4-AMINO-5-(3-METHOXYPHENYL)-7H-PYRROLO[2,3-D]PYRIMIDIN-7-YL]BENZYL}PIPERIDIN-4-OL (3 entities in total) |
Functional Keywords | protein tyrosine kinase, transferase |
Biological source | Homo sapiens (human) |
Cellular location | Cell membrane: P12931 |
Total number of polymer chains | 2 |
Total formula weight | 65713.45 |
Authors | Breitenlechner, C.B.,Kairies, N.A.,Honold, K.,Scheiblich, S.,Koll, H.,Greiter, E.,Koch, S.,Schaefer, W.,Huber, R.,Engh, R.A. (deposition date: 2005-01-27, release date: 2006-01-27, Last modification date: 2023-10-25) |
Primary citation | Breitenlechner, C.B.,Kairies, N.A.,Honold, K.,Scheiblich, S.,Koll, H.,Greiter, E.,Koch, S.,Schaefer, W.,Huber, R.,Engh, R.A. Crystal structures of active SRC kinase domain complexes J.Mol.Biol., 353:222-231, 2005 Cited by PubMed: 16168436DOI: 10.1016/j.jmb.2005.08.023 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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