1Y0S
Crystal structure of PPAR delta complexed with GW2331
Summary for 1Y0S
Entry DOI | 10.2210/pdb1y0s/pdb |
Descriptor | Peroxisome proliferator activated receptor delta, IODIDE ION, (2S)-2-(4-[2-(3-[2,4-DIFLUOROPHENYL]-1-HEPTYLUREIDO)ETHYL]PHENOXY)-2-METHYLBUTYRIC ACID, ... (5 entities in total) |
Functional Keywords | ppar, hormone-growth factor receptor complex, hormone/growth factor receptor |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 2 |
Total formula weight | 65162.15 |
Authors | Takada, I.,Yu, R.T.,Xu, H.E.,Xu, R.X.,Lambert, M.H.,Montana, V.G.,Kliewer, S.A.,Evans, R.M.,Umesono, K. (deposition date: 2004-11-16, release date: 2005-03-29, Last modification date: 2023-08-23) |
Primary citation | Takada, I.,Yu, R.T.,Xu, H.E.,Lambert, M.H.,Montana, V.G.,Kliewer, S.A.,Evans, R.M.,Umesono, K. Alteration of a Single Amino Acid in Peroxisome Proliferator-Activated Receptor-alpha (PPARalpha) Generates a PPAR delta Phenotype MOL.ENDOCRINOL., 14:733-740, 2000 Cited by PubMed: 10809235DOI: 10.1210/me.14.5.733 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.65 Å) |
Structure validation
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