1XVP
crystal structure of CAR/RXR heterodimer bound with SRC1 peptide, fatty acid and CITCO
Summary for 1XVP
Entry DOI | 10.2210/pdb1xvp/pdb |
Related | 1XV9 |
Descriptor | Retinoic acid receptor RXR-alpha, Orphan nuclear receptor NR1I3, nuclear receptor coactivator 1 isoform 1, ... (6 entities in total) |
Functional Keywords | car, rxr, citco, src1, dna binding protein |
Biological source | Homo sapiens (human) More |
Cellular location | Nucleus: Q14994 P19793 |
Total number of polymer chains | 8 |
Total formula weight | 117034.52 |
Authors | Xu, R.X.,Lambert, M.H.,Wisely, B.B.,Warren, E.N.,Weinert, E.E.,Waitt, G.M.,Williams, J.D.,Moore, L.B.,Willson, T.M.,Moore, J.T. (deposition date: 2004-10-28, release date: 2004-12-28, Last modification date: 2024-02-14) |
Primary citation | Xu, R.X.,Lambert, M.H.,Wisely, B.B.,Warren, E.N.,Weinert, E.E.,Waitt, G.M.,Williams, J.D.,Collins, J.L.,Moore, L.B.,Willson, T.M.,Moore, J.T. A Structural Basis for Constitutive Activity in the Human CAR/RXRalpha Heterodimer. Mol.Cell, 16:919-928, 2004 Cited by PubMed: 15610735DOI: 10.1016/j.molcel.2004.11.042 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
Download full validation report