1XUH
TRYPSIN-KETO-BABIM-CO+2, PH 8.2
Summary for 1XUH
Entry DOI | 10.2210/pdb1xuh/pdb |
Descriptor | TRYPSIN, COBALT (II) ION, CALCIUM ION, ... (6 entities in total) |
Functional Keywords | complex, trypsin-cobalt-small molecule ligand, designed small molecule ligand with micromolar affinity, serine protease |
Biological source | Bos taurus (cattle) |
Cellular location | Secreted, extracellular space: P00760 |
Total number of polymer chains | 1 |
Total formula weight | 23865.71 |
Authors | Katz, B.A.,Clark, J.M.,Finer-Moore, J.S.,Jenkins, T.E.,Johnson, C.R.,Rose, M.J.,Luong, C.,Moore, W.R.,Stroud, R.M. (deposition date: 1997-10-10, release date: 1998-11-11, Last modification date: 2011-07-13) |
Primary citation | Katz, B.A.,Clark, J.M.,Finer-Moore, J.S.,Jenkins, T.E.,Johnson, C.R.,Ross, M.J.,Luong, C.,Moore, W.R.,Stroud, R.M. Design of potent selective zinc-mediated serine protease inhibitors. Nature, 391:608-612, 1998 Cited by PubMed: 9468142DOI: 10.1038/35422 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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