1XO2

Crystal structure of a human cyclin-dependent kinase 6 complex with a flavonol inhibitor, fisetin

Summary for 1XO2

Entry DOI	10.2210/pdb1xo2/pdb
Related	1jow
Descriptor	Cyclin, Cell division protein kinase 6, 3,7,3',4'-TETRAHYDROXYFLAVONE (3 entities in total)
Functional Keywords	human cyclin-dependent kinase 6, fisetin, cell cycle-transferase complex, cell cycle/transferase
Biological source	Saimiriine herpesvirus 2 (Herpesvirus saimiri) More
Total number of polymer chains	2
Total formula weight	64017.98
Authors	Lu, H.S.,Chang, D.J.,Baratte, B.,Meijer, L.,Schulze-Gahmen, U. (deposition date: 2004-10-05, release date: 2005-03-01, Last modification date: 2023-08-23)
Primary citation	Lu, H.S.,Chang, D.J.,Baratte, B.,Meijer, L.,Schulze-Gahmen, U. Crystal Structure of a Human Cyclin-Dependent Kinase 6 Complex with a Flavonol Inhibitor, Fisetin. J.Med.Chem., 48:737-747, 2005 Cited by PubMed: 15689157 DOI: 10.1021/jm049353p PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.9 Å)

Structure validation