1XNI

Tandem Tudor Domain of 53BP1

Summary for 1XNI

• Entry DOI: 10.2210/pdb1xni/pdb
• Descriptor: Tumor suppressor p53-binding protein 1 (1 entity in total)
• Functional Keywords: beta-barrel, bent beta-sheet, cell cycle
• Biological source: Homo sapiens (human)
• Cellular location: Nucleus: Q12888
• Total number of polymer chains: 10
• Total formula weight: 134472.31

Authors

Huyen, Y.,Zgheib, O.,DiTullio Jr., R.A.,Gorgoulis, V.G.,Zacharatos, P.,Petty, T.J.,Sheston, E.A.,Mellert, H.S.,Stavridi, E.S.,Halazonetis, T.D. (deposition date: 2004-10-05, release date: 2004-11-30, Last modification date: 2024-02-14)

• Primary citation: Huyen, Y.,Zgheib, O.,DiTullio Jr., R.A.,Gorgoulis, V.G.,Zacharatos, P.,Petty, T.J.,Sheston, E.A.,Mellert, H.S.,Stavridi, E.S.,Halazonetis, T.D.; Methylated lysine 79 of histone H3 targets 53BP1 to DNA double-strand breaks; Nature, 432:406-411, 2004; PubMed: 15525939; DOI: 10.1038/nature03114

Experimental method

X-RAY DIFFRACTION (2.8 Å)