1XBC
Crystal structure of the syk tyrosine kinase domain with Staurosporin
Summary for 1XBC
Entry DOI | 10.2210/pdb1xbc/pdb |
Related | 1XBA 1XBB |
Descriptor | Tyrosine-protein kinase SYK, STAUROSPORINE (3 entities in total) |
Functional Keywords | staurosporine, syk, spleen typrosine kinase, active conformation, structural genomics, structural genomix, transferase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 34350.54 |
Authors | Badger, J.,Atwell, S.,Adams, J.M.,Buchanan, M.D.,Feil, I.K.,Froning, K.J.,Gao, X.,Hendle, J.,Keegan, K.,Leon, B.C.,Muller-Deickmann, H.J.,Nienaber, V.L.,Noland, B.W.,Post, K.,Rajashankar, K.R.,Ramos, A.,Russell, M.,Burley, S.K.,Buchanan, S.G. (deposition date: 2004-08-30, release date: 2004-11-02, Last modification date: 2024-02-14) |
Primary citation | Atwell, S.,Adams, J.M.,Badger, J.,Buchanan, M.D.,Feil, I.K.,Froning, K.J.,Gao, X.,Hendle, J.,Keegan, K.,Leon, B.C.,Muller-Deickmann, H.J.,Nienaber, V.L.,Noland, B.W.,Post, K.,Rajashankar, K.R.,Ramos, A.,Russell, M.,Burley, S.K.,Buchanan, S.G. A novel mode of Gleevec binding is revealed by the structure of spleen tyrosine kinase J.Biol.Chem., 279:55827-55832, 2004 Cited by PubMed: 15507431DOI: 10.1074/jbc.M409792200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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